BrainBits Tissue: Customer Publications

Tissue

• Evaluation of multi-well microelectrode arrays for neurotoxicity screening using a chemical training set.  (PMID: 22652317)
• Improving the transfection efficiency of post-mitotic neurons (PMID:  20657731)
• Levetiracetam protects hippocampal neurons in culture against hypoxia-induced injury          (PMID: 21526502)
• Block of Na+ currents and suppression of action potentials in embryonic rat dorsal root ganglion neurons by ranolazine (PMID:  22313527)
• Spectral characterization of the voltage-sensitive dye di-4-ANEPPDHQ applied to probing live primary and immortalized neurons (PMID:  19158915)
• 96-well electroporation method for transfection of mammalian central neurons (PMID: 17140120)
• Chondroitin sulfate-binding peptides block chondroitin 6-sulfate inhibition of cortical neurite growth  (PMID:  20450957)
• High-throughput transfection of differentiated primary neurons from rat forebrain (PMID: 22403411)
• Acid sensing ion channel (ASIC) inhibitors exhibit anxiolytic-like activity in preclinical pharmacological models (PMID:   18949460)
• Amyloid-beta-induced toxicity of primary neurons is dependent upon differentiation-associated increases in tau and cyclin-dependent kinase 5 expression (PMID:  14720205)
• Novel Cell and Tissue Acquisition System (CTAS): microdissection of live and frozen brain tissues (PMID:  22855692)
• The nonkinase phorbol ester receptor alpha 1-chimerin binds the NMDA receptor NR2A subunit and regulates dendritic spine density (PMID:  16221859)
• Real-time visualization of cytoplasmic calpain activation and calcium deregulation in acute glutamate excitotoxicity (PMID:  19493161)
• Ultrasound induced increase in excitability of single neurons (PMID:  19163650)
• Quantitative microplate-based respirometry with correction for oxygen diffusion           (PMID:  19555051)
• Dynamics of bidirectional transport of Arc mRNA in neuronal dendrites (PMID:  17120280)
• Acute Treatment With Herbal Extracts Provides Neuroprotective Benefits in In Vitro and In Vivo Stroke Models, Characterized by Reduced Ischemic Cell Death and Maintenance of Motor and Neurological Functions (PMID:  21379315)
• Luteinizing hormone receptor mediates neuronal pregnenolone production via up-regulation of steroidogenic acute regulatory protein expression (PMID:  17241129)
• Src kinase inhibition decreases thrombin-induced injury and cell cycle re-entry in striatal neurons (PMID:  18343677)
• Enhanced polarization of embryonic hippocampal neurons on micron scale electrospun fibers (PMID:  19353562)
• Polypyrrole-coated electrospun PLGA nanofibers for neural tissue applications              (PMID:  19501901)
• Neuronal targeting, internalization, and biological activity of a recombinant atoxic derivative of botulinum neurotoxin A (PMID:  21284937)
• Human Neuronal Cells Possess Functional Cytoplasmic and TLR-Mediated Innate Immune Pathways Influenced by Phosphatidylinositol-3 Kinase Signaling (PMID:  20483728)
• Polarization of hippocampal neurons with competitive surface stimuli: contact guidance cues are preferred over chemical ligands (PMID:  17251152)
• Hippocampal neurons respond uniquely to topographies of various sizes and shapes      (PMID:  20823503)
• Impaired balance of mitochondrial fission and fusion in Alzheimer's disease                 (PMID:  19605646)
• Cocaine- and amphetamine-regulated transcript peptide modulation of voltage-gated Ca2+ signaling in hippocampal neurons (PMID:  11567037)
• The inhaled anesthetic, isoflurane, enhances Ca2+-dependent survival signaling in cortical neurons and modulates MAP kinases, apoptosis proteins and transcription factors during hypoxia (PMID:  16861427)
• Amyloid-β-Derived Diffusible Ligands Cause Impaired Axonal Transport of Mitochondria in Neurons (PMID:  20160460)
• Uniform polarity microtubule assemblies imaged in native brain tissue by second-harmonic generation microscopy (PMID:  12766225)
• Isolation and culture of adult neurons and neurospheres (Nature Protocols 2, 1490 - 1498 (2007))
• A three-dimensional neural spheroid model for capillary-like network formation (Science Direct: 28143748)
• Axon Outgrowth of Rat Embryonic Hippocampal Neurons in the Presence of an Electric Field (PMID: 27529437)
• Iterative Focused Screening with Biological Fingerprints Identifies Selective Asc-1 Inhibitors Distinct from Traditional High Throughput Screening. (PMID: 28032990)
• Engineering cortical neuron polarity with nanomagnets on a chip. (PMID: 25801533)
• Induction of Calcium Influx in Cortical Neural Networks by Nanomagnetic Forces (PMID: 26805612)
• Mfn2 Protects Dopaminergic Neurons Exposed to Paraquat Both in vitro and in vivo: Implications for Idiopathic Parkinson's Disease (PMID: 28215578)
• Chondroitin Sulfate Glycosaminoglycan Hydrogels Create Endogenous Niches for Neural Stem Cells (PMID: 26440046)
• Separation and assisted patterning of hippocampal neurons from glial cells using positive dielectrophoresis (PMID: 26009274)
• Multi-electrode array capable of supporting precisely patterned hippocampal neuronal networks (PMID: 25653057)
• Immersion lithographic patterning of electrospun nanofibers for carbon nanofibrous microelectrode arrays (ISSN: 1057-7157)
• Actomyosin Dynamics Determine the Extension and Retraction of Filopodia on Neuronal Dendrites (BIORXIV)
• Investigating brain functional evolution and plasticity using microelectrode array technology (SCIENCE DIRECT)
• A Nuclear Attack on Traumatic Brain Injury: Sequestration of Cell Death in the Nucleus (PMID: 26842647)
• The effect of apolipoprotein E4 on synchronous neural interactions in brain cultures (PMID: 25869740)
• HAMr: A Mechanical Impactor for Repeated Dynamic Loading of In vitro Neuronal Networks (SPRINGER LINK)
• An in vitro method to manipulate the direction and functional strength between neural populations (PMID: 26236198)
• Feed-Forward Propagation of Temporal and Rate Information between Cortical Populations during Coherent Activation in Engineered In Vitro Networks (PMID: 27147977)
• Degradation of the electrospun silica nanofiber in a biological medium for primary hippocampal neuron - effect of surface modification (PMID: 27013873)
• Estimation of the physical properties of neurons and glial cells using dielectrophoresis crossover frequency (PMID: 27394429)
• Function coupling of otoferlin with GAD65 acts to modulate GABAergic activity (PMID: 25701657)
• Anchoring of protein kinase A by ERM (ezrin-radixin-moesin) proteins is required for proper netrin signaling through DCC (deleted in colorectal cancer) (PMID: 25575591)
• Deletion of a Predicted β-Sheet Domain within the Amino Terminus of Herpes Simplex Virus Glycoprotein K Conserved among Alphaherpesviruses Prevents Virus Entry into Neuronal Axons. (PMID: 26656706)
• 3D-printing of transparent bio-microfluidic devices in PEG-DA (PMID: 27217203)
• Modulating motility of intracellular vesicles in cortical neurons with nanomagnetic forces on-chip (PMID: 28164203)
• Imaging GPCRs trafficking and signaling with total internal reflection fluorescence microscopy in cultured neurons (PMID: 26928537)
• Real-time imaging of mu opioid receptors by total internal reflection fluorescence microscopy (PMID: 25293317)
• Combined Optogenetic and Chemogenetic Control of Neurons (PMID: 26965125)
• Sustained elevation of activity of developing neurons grown on polyimide microelectrode arrays (MEA) in response to ultrasound exposure (SPRINGER LINK)
• Septin 9 interacts with kinesin KIF17 and interferes with the mechanism of NMDA receptor cargo binding and transport (PMID: 26823018)
• Nerve Growth Factor Regulates Transient Receptor Potential Vanilloid 2 via Extracellular Signal-Regulated Kinase Signaling To Enhance Neurite Outgrowth in Developing Neurons (PMID: 26416880)
• Nerve Growth Factor Regulates Transient Receptor Potential Vanilloid 2 via Extracellular Signal-Regulated Kinase Signaling To Enhance Neurite Outgrowth in Developing Neurons (PMID: 26416880)
• Discovery and Characterization of Nonpeptidyl Agonists of the Tissue-Protective Erythropoietin Receptor (PMID: 26018904)
• Upward synaptic scaling is dependent on neurotransmission rather than spiking (PMID: 25751516)
• VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease. (PMID: 27561680)
• Action potential block in neurons by infrared light (PMID: 27990450 )
• 1,3-Dinitrobenzene neurotoxicity - Passage effect in immortalized astrocytes (PMID: 26769196)
• Study of the protective effects of nootropic agents against neuronal damage induced by amyloid-beta (fragment 25-35) in cultured hippocampal neurons (PMID: 25712658 )
• Anthropogenic Radio-Frequency Electromagnetic Fields Elicit Neuropathic Pain in an Amputation Model (PMID: 26760033)
• TMEM175 deficiency impairs lysosomal and mitochondrial function and increases α-synuclein aggregation (PMID: 28193887)
• Imaging mRNA and protein interactions within neurons (PMID: 28223507)
• Short Infrared Laser Pulses Block Action Potentials in Neurons (Spie Digital Library)
• The role of membrane dynamics in electrical and infrared neural stimulation (Spie Digital Library)
• Interfacing neurons on carbon nanotubes covered with diamond (Pubs)
• Cleaning patch-clamp pipettes for immediate reuse (PMID: 27725751)
• Cell Injury-Induced Release of Fibroblast Growth Factor 2: Relevance to Intracerebral Mesenchymal Stromal Cell Transplantations (PMID: 25873141)
• Vitamin K2 Prevents Beta Amyloid Peptide and Vitamin K3-induced Cell Death (fasebj)
• Three-Dimensional Neural Spheroid Culture: An In Vitro Model for Cortical Studies (PMID: 26414693)
• Morphometric assessment of toxicant induced neuronal degeneration in full and restricted contact co-cultures of embryonic cortical rat neurons and astrocytes: using m-Dinitrobezene as a model neurotoxicant (PMID: 25553915)
• A Neuronal Activity-Dependent Dual Function Chromatin-Modifying Complex Regulates Arc Expression(1,2,3) (PMID: 26464965)
• Olfactory ensheathing cell-neurite alignment enhances neurite outgrowth in scar-like cultures (PMID: 25863021)
• Neurotoxic mechanisms of paclitaxel are local to the distal axon and independent of transport defects (PMID: 27894788)
• Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in giant axonal neuropathy (PMID: 27000625)
• Using Cultured Mammalian Neurons to Study Cellular Processes and Neurodegeneration: A Suite of Undergraduate Lab Exercises (PMID: 27385922)
• Fluorescence Activated Cell Sorting (FACS) and Gene Expression Analysis of Fos-expressing Neurons from Fresh and Frozen Rat Brain Tissue (PMID: 27685012)
• A dynamic formin-dependent deep F-actin network in axons (PMID: 26216902 )
• Facilitation of axon regeneration by enhancing mitochondrial transport and rescuing energy deficits (PMID: 27268498 )
• GluN2B-Containing NMDA Receptors Regulate AMPA Receptor Traffic through Anchoring of the Synaptic Proteasome (PMID: 26041915)
• A Bright and Fast Red Fluorescent Protein Voltage Indicator That Reports Neuronal Activity in Organotypic Brain Slices (PMID: 26911693)
• Gene-Silencing Screen for Mammalian Axon Regeneration Identifies Inpp5f (Sac2) as an Endogenous Suppressor of Repair after Spinal Cord Injury (PMID: 26203138)
• Alcohol Regulates BK Surface Expression via Wnt/β-Catenin Signaling (PMID: 27733613)
• G2019S-LRRK2 Expression Augments α-Synuclein Sequestration into Inclusions in Neurons (PMID: 27413152)
• Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8. (PMID: 26989142)
• Hydrophobically Modified siRNAs Silence Huntingtin mRNA in Primary Neurons and Mouse Brain (PMID: 26623938)
• Docosahexaenoic Acid Conjugation Enhances Distribution and Safety of siRNA upon Local Administration in Mouse Brain. (PMID: 28131259)
• Sequential Elution Interactome Analysis of the Mind Bomb 1 Ubiquitin Ligase Reveals a Novel Role in Dendritic Spine Outgrowth (PMID: 25931508)
• Exosome-mediated Delivery of Hydrophobically Modified siRNA for Huntingtin mRNA Silencing (PMID: 27506293)
• Efficient genome editing in the mouse brain by local delivery of engineered Cas9 ribonucleoprotein complexes (PMID: 28191903)
• The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity (PMID: 27348499)
• Parkinson's disease-associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes (PMID: 26618722)
• High-performance probes for light and electron microscopy (PMID: 25915120)
• GDF10 is a signal for axonal sprouting and functional recovery after stroke (PMID: 26502261)
• Aβ and NMDAR activation cause mitochondrial dysfunction involving ER calcium release (PMID: 25442114)
• Multiple domains in the C-terminus of NMDA receptor GluN2B subunit contribute to neuronal death following in vitro ischemia (PMID: 26581639)
• Increased 5-hydroxymethylation levels in the sub ventricular zone of the Alzheimer's brain (Science Direct)
• Activity-Dependent Regulation of Distinct Transport and Cytoskeletal Remodeling Functions of the Dendritic Kinesin KIF21B (PMID: 27817978)
• The Mammalian-Specific Protein Armcx1 Regulates Mitochondrial Transport during Axon Regeneration (PMID: 28009275)
• Cholinesterase Inhibitor Donepezil Increases Mitochondrial Biogenesis through AMP-Activated Protein Kinase in the Hippocampus (PMID: 27002982)
• MiR-21 and miR-222 inhibit apoptosis of adult dorsal root ganglion neurons by repressing TIMP3 following sciatic nerve injury (PMID: 25484256)
• Sera from children with autism induce autistic features which can be rescued with a CNTF small peptide mimetic in rats (PMID:25769033)
• Induction of Multiple miR-200/182 Members in the Brains of Mice Are Associated with Acute Herpes Simplex Virus 1 Encephalitis. (PMID: 28045967)
• Structural and Functional Interactions between Transient Receptor Potential Vanilloid Subfamily 1 and Botulinum Neurotoxin Serotype A (PMID: 26745805)
• MiR-21 in Extracellular Vesicles Leads to Neurotoxicity via TLR7 Signaling in SIV Neurological Disease. (PMID: 26154133)
• Spatial temperature gradients guide axonal outgrowth (PMID: 27460512)
• 8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions. (PMID: 26912170)
• A cell-penetrating peptide for inhibiting MAPKAP Kinase 2-mediated inflammatory cytokine release following glial cell activation (Scrip)
• Modulating motility of intracellular vesicles in cortical neurons with nanomagnetic forces on-chip. (PMCID: PMC5400667)